clinical implications of recent trials on anticoagulation in patients with atrial fibrillation
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منابع مشابه
Clinical Implications of Recent Trials on Anticoagulation in Patients with Atrial Fibrillation
The past year has seen the publication of results of the largest and arguably the most significant clinical trials of antithrombotic to prevent stroke and systemic thromboembolism in patients with atrial fibrillation (AF) (1-3). In 2011, results of two trials concerning anticoagulation in patients with AF in addition to RE-LY study were also published (4-6). Canadian AF guidelines has been upda...
متن کاملAre the results of randomized controlled trials on anticoagulation in patients with atrial fibrillation generalizable to clinical practice?
BACKGROUND Randomized trials demonstrate a clear benefit of anticoagulation in patients with atrial fibrillation at risk of stroke, but the proportion of eligible patients who are treated with anticoagulants remains low. The reluctance to treat all eligible patients with anticoagulants may be due to studies in clinical practice showing variable risk-benefit, raising concerns about application t...
متن کاملAnticoagulation in Atrial Fibrillation
Atrial fibrillation (AF) is the most commonly occurring arrhythmia. An antithrombotic agent is considered mandatory as part of the management in most patients with AF. It has been conclusively demonstrated that long-term anticoagulation therapy can significantly reduce the risk of stroke in patients with non-valvular AF. While vitamin K antagonists (VKAs) such as warfarin are highly effective, ...
متن کاملAnticoagulation in atrial fibrillation
Atrial fibrillation (AF) affects approximately 300,000 Australians and has a growing prevalence. It is associated with high rates of death and disability. The majority of people with AF are eligible to be treated with anticoagulant medications, but practice is often inadequate, leaving many people at risk of stroke. Until recently, the only antithrombotics available to prevent stroke in people ...
متن کاملClinical Significance of P Wave Dispersion in Prediction of Atrial Fibrillation in Patients with Acute Myocardial Infarction
Background: P wave dispersion (PWD) is defined as the difference between the maximum P wave duration (Pmax) and the minimum P wave duration (Pmin) in 12-leads of the surface electrocardiography. The aim of this study was to evaluate the values of PWD during atrial fibrillation (AF) after acute myocardial infarction (AMI). Methods: We prospectively evaluated atrial rhythms of 350 patients (251 m...
متن کاملInterrupting anticoagulation in patients with nonvalvular atrial fibrillation.
Three target-specific oral anticoagulants (TSOACs)-dabigatran, rivaroxaban, and apixaban-have been approved by the FDA to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation; however, no agents are currently approved to reverse the anticoagulant effects of these TSOACs in cases of active bleeding. This review discusses the benefits and risks of these...
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عنوان ژورنال:
research in cardiovascular medicineجلد ۱، شماره ۱، صفحات ۳-۹
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